Professional Services and Consulting

Other, Business development, Financial services, Information provider, Technology transfer

LifeBridge Health BioIncubator is Maryland's hospital-based (Sinai Hospital) bioIncubator, and serves emerging biotech and life sciences companies by providing lab and office space, access to research equipment, connection to LifeBridge Health physicians and personnel, and innovation support, networking opportunities, access to grant-writing and funding support, and more. The network also includes more than 130 outpatient centers, urgent care facilities, and wellness programs across Maryland. LifeBridge Health also invests in research and innovation, running the Sinai Hospital BioIncubator to support biotech startups.
In partnership with CareFirst’s Healthworx, launched 1501 Health, a virtual incubator for digital health companies.

Public / Non-Profit Organizations / Medical Facilities

Other, Governmental organization

The Maryland SBDC promotes the viability and expansion of businesses owned by economically and socially disadvantaged entrepreneurs, and also provides intellectual property and technology commercialization assistance to businesses in the technology industry. The Maryland Small Business Development Center (SBDC) offers free individualized consulting, from startup to established businesses, also offers comprehensive training programs, from startup business to executive training classes.

Public / Non-Profit Organizations / Medical Facilities

Industry association

Maryland Tech Council Mentoring Services provides structured, team-based mentoring to Maryland technology and life-sciences startups. The program connects entrepreneurs with experienced business and industry advisors who provide guidance on areas such as business strategy, fundraising, commercialization, product development, intellectual property, finance, and organizational growth.

Digital Health

Healthcare Mobile Communication, Patient Engagement, Population Health Management, Remote Monitoring, Telehealth, Artificial intelligence (AI)

Endocrine, nutritional and metabolic diseases / endocrinology, Mental and behavioural disorders / psychiatry /psychology, Diseases of the nervous system / neurology, Diseases of the eye / ophthalmology, Cardiovascular / cardiology, Respiratory / pulmonology, Pregnancy, childbirth and the puerperium / obstetrics

MEMOTEXT is a clinical-grade digital health platform and marketplace for building, validating, deploying, and scaling digital patient engagement and clinical decision-support programs. Through mtxt.ai, the company supports clinical, research, and commercial teams in moving from initial concepts to protocols and prototypes, while MEMOTEXT provides secure infrastructure, real-world deployment capabilities, and a marketplace for validated patient engagement solutions.

Public / Non-Profit Organizations / Medical Facilities

University, Research facility

Mtech Ventures is a University of Maryland incubator for technology-based innovations commercialized at the university. Mtech Ventures helps early-stage startups survive the critical period in their development between conducting customer discovery and raising their first round of venture capital. The Mtech Ventures facility offers affordable space and hands-on mentoring for early stage companies. Companies involved in the program also benefit from the extensive facilities and services available from the University System of Maryland, one of the country’s largest public research and teaching systems.

Biotechnology - Therapeutics and Diagnostics

Small molecules

Neoplasms / cancer / oncology

Natsar Pharmaceuticals is an applied research and drug development company focused on the development of novel treatments for cancer and other diseases. The company is currently preparing for a clinical trial of RK-33 in the treatment of lung, breast, brain, and soft tissue (sarcoma) cancer. RK-33 is a first-in-class, a small molecule that binds DDX3, an RNA helicase shown to be elevated in aggressive and metastatic cancers.

RK-33’s novel and unique mechanism of action focuses on tumor DNA repair and cellular bioenergetics, shutting down the high metabolic growth and division phase of cancerous cells without affecting normal cell growth. RK-33 has been studied and shown to be effective in several non-clinical tumor models including: sarcomas, brain, pancreatic, and breast cancer bone metastasis. The company's initial clinical focus is sarcomas, an area of extremely high unmet need.

In sarcomas, DDX-3 expression is nearly ubiquitous across sarcoma subtypes, indicating RK-33 is potentially applicable across many/most subtypes. RK-33 has been shown in non-clinical studies to suppress tumor growth in mouse sarcoma xenograft models, both as a standalone treatment and when combined with radiation. RK-33 combined with radiation demonstrated a synergistic effect in reducing tumor growth in a PDX model of sarcoma.

Biotechnology - Therapeutics and Diagnostics

Cell therapy, Gene therapy, Immunotherapy

Neoplasms / cancer / oncology, Diseases of the blood and blood-forming organs & immune disorders / hematology / immunology

Neomics Pharmaceuticals is a preclinical-stage biotech company developing novel cell therapy to treat cancers. The company has made a breakthrough in engineering high-functional third-generation chimeric co-stimulatory receptors in T cells. The technology lays the foundation to develop anti-BCMA CAR T cells to treat multiple myeloma and ICS T cells to treat broad types of solid tumors that are resistant or relapsed from ICI treatment. The proprietary third-generation platform has a potential to bring a fundamental change to the development of T cell products. By replacing with different extracellular domains targeting various proven, validated, or novel targets from hematology and solid tumors, the success of the third-generation CAR platform will lay the foundation for a newer generation of CAR T and TCR T pipeline with a clear edge on clinical efficacy.

Biotechnology - Therapeutics and Diagnostics

Proteins, Small molecules

Mental and behavioural disorders / psychiatry /psychology, Diseases of the nervous system / neurology, Cardiovascular / cardiology

NeuroImpact Therapeutics is a preclinical biotechnology company developing next-generation small-molecule therapeutics for neurological and cardiovascular diseases. The company has built an AI-enabled drug discovery platform that combines cryo-electron microscopy (cryo-EM), electrophysiology, protein biochemistry, and computational drug design to develop tissue-specific ion channel modulators. By precisely targeting the molecular mechanisms underlying disease, NeuroImpact Therapeutics aims to improve treatment efficacy while minimizing off-target side effects. The company's initial pipeline is focused on epilepsy, with the platform designed to support the development of therapies for a broad range of disorders involving ion channel dysfunction.

Public / Non-Profit Organizations / Medical Facilities

Other

The Novella Center for Entrepreneurship (“NCE”) by Conscious Venture Lab is a nonprofit organization. NCE creates partnerships and programming to train entrepreneurs how to build companies that matter. The company exposes entrepreneurs, early-stage founders, and CEOs to the tenets of stakeholder theory and conscious capitalism, demonstrating that managing a business for all stakeholders creates both societal and financial value.

Public / Non-Profit Organizations / Medical Facilities

Other

Prince George's County Economic Development Corporation (PGCEDC) is a nonprofit economic development organization supporting business growth and economic development in Prince George's County, Maryland. The organization works to attract, retain and expand businesses through business development assistance, site selection, financial incentives, workforce support and connections to public and private resources. PGCEDC also provides small business counseling, entrepreneurship and incubation programs, international business development, export and foreign direct investment support, procurement assistance and access to financing resources.

Public / Non-Profit Organizations / Medical Facilities

Science / Technology park, University

The Rita Rossi Colwell Center is an architecturally striking 250,000 square foot multi-functional facility in Baltimore’s Inner Harbor. The firm is a hub for Maryland’s blossoming tech-startup culture and offers prestigious office spaces, wet labs, meeting rooms, and inspiring event spaces.

Public / Non-Profit Organizations / Medical Facilities

Science / Technology park

The Rockville Innovation Center offers a nationally-recognized incubator program with a full menu of resources and support services to help entrepreneurs develop a successful business venture. The company offers 23,000 square feet of flexible office space to stimulate business growth for international, professional service, and advanced technology companies.

Public / Non-Profit Organizations / Medical Facilities

Foundation

The goal of the Shore Hatchery is to reward individuals for their entrepreneurial efforts in the creation and growth of businesses with the potential of positively impacting regional employment within three years. The Perdue School of Business Philip E. & Carol R. Ratcliffe Foundation Shore Hatchery is a bi-annual Mid-Atlantic business competition.

Professional Services and Consulting

Business development, Management consulting, Technology transfer

The Center for Advancing Innovation (CAI) is a global public-private, non-profit partnership focused on research assets: accelerate and increase the volume of technology commercialization to make valuable research assets available. CAI's mission is to accelerate and increase the volume of research commercialization in support of business growth to ignite entrepreneurship, bolster the global economy, and maximize the commercial and knowledge-based potential of promising inventions.

Investor

Foundation

The EDGE accelerator offers education to advance the life cycle of a startup. The Edge is a robust 12-week community growth accelerator program designed for aspiring entrepreneurs and startups. The 12-week program is a boot camp that includes customized mentorship, expert guidance and access to valuable resources and programming to help entrepreneurs speed the learning curve and avoid making costly mistakes.

Public / Non-Profit Organizations / Medical Facilities

Science / Technology park

Frederick Innovative Technology Center, Inc. (FITCI) is a non-profit business incubator and accelerator that provides office space, laboratory facilities, and business support services to local entrepreneurs. The firm supports early-stage companies in biotechnology, information technology, and renewable energy through office and wet lab space, business services, and strategic support.

Investor

Venture capital fund

Tonic Bioventures is a life sciences Investment fund and looking to invest in early stage biotech and medical device companies that have a proof-of-concept and non-diluted funding. They invest and nurture the growth of these companies to an exit model of out-licensing to corporate strategics and achieve a faster than average return of investment than most VC fund.

Investor

Venture capital fund

University of Maryland Ventures (UM Ventures) is a technology transfer and commercialization unit of the University of Maryland, Baltimore and the University of Maryland, College Park. The firm manages intellectual property, supports licensing activities, and facilitates collaboration between university researchers and external organizations. The unit also coordinates entrepreneurship-related programs across both campuses.

Public / Non-Profit Organizations / Medical Facilities

Institute, Research facility

The University of Maryland BioPark’s BioInnovation Center (BIC) provides pre-built wet labs and office space for emerging companies. The BioInnovation Center provide companies that require their own dedicated wet lab and/or office space, but may not be ready to build out their own space or commit to a long-term lease.

Investor

Private investor / family office, Venture capital fund

Wearable Tech Ventures (WTV) is a 501(c)(3) non-profit organization focused on supporting the development and commercialization of wearable technology. The organization operates through three core programs: Connect (offering mentorship and network access to national accelerators), Train (providing AI and wearable technology training initiatives for youth and emerging innovators), and Fund (facilitating access to investors, corporate partners, and grant opportunities). WTV specifically targets underrepresented founders and aims to support 100 wearable startups by 2030 across sectors including digital health, fashion tech, defense, and employee safety.